Prednisolone: instructions for use, indications

A Few products can boast such a number of indications and possibilities, but do not have many products such as serious side effects, contraindications, warnings.

So what kind of a drug – prednisolone?

Prednisone is the hormonal drug.

Many of us at the mention of the term “hormone preparation” immediately eliminates the desire to use it. However, do not rush to turn over the page.

With skillful use of hormonal drugs can be of great benefit. Thus it is possible to minimize unwanted effects from the use of such means. Prednisolone acts on the central nervous system and through this influence covers the whole human body.

Prednisolone reduces inflammation, inhibits the work of immunity, relieves allergic reactions, as well as displays the toxic substances from the body.

Prednisolone affect the operation of certain parts of the brain and inhibits the production of certain hormones.

This influence affects the chemical composition of the blood. It reduces the number of lymphocytes and eosinophils – indicators of inflammation in the body, but it increases the number of red blood cells.

Through the effect on the production of proteins in the body, prednisolone inhibits allergic reactions and inflammatory processes. Assign prednisolone with joint problems, including diseases of the joints, provoked by infection, bronchial asthma, blood cancer. In violation of the chemical composition of the blood, caused by infections.

A good effect is the use of prednisolone for various skin diseases of internal nature, such as eczema, psoriasis and neurodermatitis.

Tests were conducted on the effectiveness of prednisolone for liver and kidney. Due to the fact that suppresses the activity of macrophages of prednisolone and operation of local immunity, it can be used to treat certain autoimmune diseases.

If you have an eye disease such as conjunctivitis noninfectious etiology, inflammation in the cornea, sclera, or the eyeball.

If you have had any surgery on the eyeball or injure him, prednisolone can reduce inflammation and promote rapid healing.

Prednisolone perfectly absorbed by the body. He quickly enters the bloodstream and the highest number in the blood observed after half an hour after administration. Processed prednisolone by the liver, and is evacuated from the body three hours later.

If large quantities of the drug can greatly increase body weight, disrupt the adrenal glands, in the stomach increases the synthesis of gastric juice, which can lead to development of ulcers.

The use of prednisone displays salts of certain elements from the body that can trigger the development of osteoporosis in adults and growth disorders in children.

Perhaps a persistent elevation of blood pressure, blood clotting increases. The use of prednisone may be adversely affected, and to the eyes. This results in occurrence of cataracts and glaucoma latent. Due to the fact that prednisolone inhibits the immune system, any, even the smallest scratch can heal for a long time, can start vesicate.

You can often get sick colds and viral diseases, as well as any other infectious disease.

With prolonged use at high doses may impair the central nervous system, which is expressed in mental disorders. Use prednisolone only on prescription and under his constant supervision. Then the number of side effects will be reduced to a minimum.

Before use, you need to consult with a specialist.

Prednisolone for allergies: indications for use and side effects

Currently, about 20% of the population suffers from allergies. It can be caused by anything. Dust, flowering plants, food, even the sun, all these factors can provoke this unpleasant disease. Pharmacists have been developing new drugs for many years. Among them, Prednisolone has a good therapeutic effect.

This is an exceptional medicine that copes well with allergic reactions. Prednisolone eliminates inflammation, helps the immune system fight the disease, removes mucosal edema.

Release form, composition, packaging

Prednisolone is available in 4 forms – tablets, injections, ointment, drops. The tablets are white. They contain the active substance prednisolone 5 mg and additional components – starch, calcium stearate, lactose. They are packaged in blisters of 10 pieces, packed in cardboard boxes of 10, 20, 30, 50, 60, 100 tablets.

The solution for injections has a transparent color with a slight yellowish tinge. The active substance is represented by prednisolone, auxiliary agents – nicotinamide, sodium hydroxide, sodium metabisulfate, water for injection. A dark glass ampoule contains 1 ml of medicine, the packaging is plastic pallets of 3 pieces and placed in cardboard boxes.

Ointment 0.5% consists of a basic substance (per 100 g of ointment, 0.5 g of prednisolone) and auxiliary components – glycerol, petroleum jelly, stearic acid, nipagin, nipazole, emulsifier No. 1, water. Produced in tubes of 10 g. 0.5% drops are released in the form of a white suspension of 5 ml. Poured into bottles with a dispenser and placed in a cardboard package. The active ingredient is prednisolone.

Pharmacology

The drug is a synthetic steroid hormone from the subclass of corticosteroids that is produced by the adrenal cortex. This is due to its anti-inflammatory, anti-allergic, anti-exudative properties. The drug inhibits the function of white blood cells and macrophages. Stops the movement of leukocytes to the site of inflammation. Helps stabilize lysosomal cells by decreasing the concentration of proteolytic protein molecules in the inflamed area. Reduces capillary thinness.

Pharmacokinetics

When used internally, it is well absorbed from the gastrointestinal tract. The highest concentration in the blood is reached after 1.5 hours. After intravenous administration, half an hour is enough. The drug is excreted by the kidneys.

Mechanism of action

Any processes occurring in the human body are regulated by chemical reactions that are controlled by hormones. They have a similar structure and are practically the same in action. During a stressful situation, they activate protective functions, which are directed at combating the cause of overvoltage. It became known that their action: stops the destruction of cells; inhibits the effects of the immune system; reduces the adhesion of water to damaged tissues; reduces the passage of allergens by blood vessels.

Indications for use

The range of application of the medication is wide enough. It is prescribed for the following diseases:

bronchial asthma;
acute and chronic allergic diseases;
any kind of shock;
swelling of the brain;
acute adrenal insufficiency;
rheumatoid arthritis, lupus erythematosus;
eczema, dermatitis, psoriasis;
acute hepatitis, hepatic coma;
Addison’s disease;
conjunctivitis, blepharitis;
inflammation of the cornea, eyeball;
after eye surgery.

Prednisolone and Dexamethasone

If you read the instructions for the use of Dexamethasone, you can see that the indications are exactly the same. He also as Prednisolone has anti-inflammatory, anti-allergenic, anti-shock, anti-toxic effects. However, only a doctor can tell which drug is suitable in each specific case.

Instruction

The tablet form of the drug is prescribed for internal administration. It is washed down with water, while the tablet cannot be chewed. The usual adult dosage is 20-30 mg per day. Over time, it is reduced to 5-10 mg. Children’s daily dosage at the beginning of treatment assumes 2 mg of the drug per 1 kg of the child’s body weight. It is divided by 4-6 times.

Stopping treatment with this drug should take place smoothly, with a gradual decrease in the dose. Intravenous injection is allowed only when it is necessary to stop a shock attack.

For adults, Prednisolone is administered intramuscularly or given a dropper.

The injection rate should be very slow. The dosage of the drug fluctuates in numbers 1-3 ml, in critical cases it can be increased to 5-10 ml.

The introduction of the solution intramuscularly is allowed for children. The dose for the age group from 2 months to a year is 2-3 mg per kilogram of body weight.

Children from one to 14 years old are prescribed 2 mg per kg of body weight. You can repeat the injection after 30 minutes.

Drops are used 3 times a day. Usually, 2 drops of the drug are injected into one eye socket.

The ointment is applied in a thin layer to the affected area 1-3 times throughout the day.

When using the medication, you need to know some rules:

In no case do not use the drug for prophylactic purposes;
Treatment should take place under the supervision of the attending physician;
If there is an alternative method of therapy with non-steroidal drugs, Prednisolone is not used.

The price of Prednisolone

Prednisolone is a fairly inexpensive medication. Its cost ranges from 0.5-3 US dollars. This is due to the form of the drug and the amount in the package.

Terms and conditions of storage

Prednisolone is stored at a temperature not higher than +25 degrees, in a dry place where a child cannot get it. The shelf life is 24 months.

Buying Prednisolone at the pharmacy

To purchase the drug, you need to present a prescription. You can also buy Prednisolone without a prescription from your online pharmacy.

Analogs

There are drugs with similar pharmacology and application.

1. Dexamethasone. It is prescribed for almost the same diseases as Prednisolone. The price of the drug online is $ 0.5-1.

2. Hydrocortisone. It has anti-allergic, anti-inflammatory properties. The price policy of the drug is from 0.2 to 1 US dollar.